Personalized MRI
High magnetic field MRI can provide earlier detection and better therapeutic monitoring of multiple sclerosis (MS) than lower field MRI, but its use is currently limited due to the unpredictable distribution of tissue heating induced by the radio waves used to obtain an MR image. Team MS-SAR is working on hardware and software-based solutions to allow for personalized control of the MRI acquisition to avoid possible unsafe heating. In addition, this technology will also allow for the use of MRI in subjects with implanted brain electrodes.
Name & Contact
Team MS-SAR
Esra Türk esraturk@mit.edu
Project status
M+Visión project: Jan 2012 – Jun 2014
On exit from M+Visión: Support through grants held by collaborators
M+Visión follow on: Jun 2014 – Sep 2015
Sector
Antenna Design. SAR. Electromagnetic modeling. High field imaging.
Fellows
Yigitcan Eryaman, Joaquin Herraiz, Robert Kosior (original team)
Esra Türk (joined Oct 2013)
Collaborators
Antonio Hernandez-Tamames, Norberto Malpica, Engineering
URJC
Emanuele Schiavi, Applied Math
URJC
Elfar Adalstenisson, Research Lab of Electronics
MIT
Larry Wald
Martinos Center MGH
Students
Adrian Martin
Applied Math, URJC
Angel Torrado Carvajal
Engineering, URJC
Parallel Transmit Pulse Design for Patients with Deep Brain Stimulation (DBS) Leads. Eryaman Y, Guerin B, Akgun C, Herraiz J.L, Martin A, Torrado-Carvajal A, Malpica N, Hernandez-Tamames J A, Schiavi E, Adalsteinsson E, Wald LL., Magn Reson Med 73(5):1896-1903 (doi: 10.1002/mrm.25324) 2014.
Multi‐atlas and label fusion approach for patient‐specific MRI based skull estimation. Torrado‐Carvajal A, Herraiz JL, Hernandez‐Tamames JA, San Jose‐Estepar R, Eryaman Y, Rozenholc Y, Adalsteinsson E, Wald LL, Malpica N. Magn Reson Med, (doi: 10.1002/mrm.25737 ) 2015.
On the Robustness of local SAR prediction in optimal parallel transmission pulse design. Martin A, Guerin B, Eryaman Y, Herraiz JL, Adalsteinsson E, Wald LL, Schiavi E ESMRMB 2013
Use of “Dark Modes” in a Loop + Dipole Array to Reduce SAR in 7T C-Spine Imaging. Eryaman Y, Adalsteinsson E, Wald, LL. ISMRM 2013
Combined Loop + Dipole Arrays for 7 T Brain Imaging. Eryaman Y, Guérin B, Kosior R, Adalsteinsson E, Wald LL. ISMRM 2013
The Ultimate Local SAR in MRI. Eryaman Y, Guérin B, Adalsteinsson E, Wald, LL. ISMRM 2013
Parallel Transmit Pulse Design with Implant-Friendly Modes. Eryaman Y, Guérin B, Adalsteinsson E, Wald, LL. ISMRM 2013
Design of parallel transmission pulses in the presence of RF errors. Martin A, Guerin B, Eryaman Y, Herraiz JL, Gagoski B, Adalsteinsson E,Wald LL Schiavi E .Joint Annual Meeting of ISMRM-ESMRMB 2014
A Multi-Atlas and Label Fusion Approach for Patient-Specific MRI Based Skull Segmentation. Torrado-Carvajal A, Hernandez-Tamames JA, Herraiz JL, Eryaman Y, Rozenholc Y, Adalsteinsson E,Wald LL,Norberto Malpica N. Joint Annual Meeting of ISMRM-ESMRMB 2014
Automatic Segmentation Pipeline for Patient-Specific MRI Tissue Models. Torrado-Carvajal A, Hernandez-Tamames JA, Herraiz JL, Eryaman Y,Adalsteinsson E,Wald LL,Norberto Malpica N. Joint Annual Meeting of ISMRM-ESMRMB 2014
A Simulation Based Validation of a pTx Pulse Design Strategy Using Implant-Friendly Modes for Patients with DBS Implants. Eryaman Y, Guerin B, Akgun C, Herraiz JL, Martin A , Torrado-Carvajal A, Malpica N, Hernandez-Tamames JA, Schiavi E, Adalsteinsson E, Wald LL. Joint Annual Meeting of ISMRM-ESMRMB 2014
MRI planning for SAR management in pTx systems. Herraiz JL, Eryaman Y, Abaci Turk E, Torrado-Carvajal A, Martin A, Schiavi E, Guerin B, Adalsteinsson E, Wald LL, Hernandez-Tamames JA, and Malpica N Annual Meeting of ISMRM 2015
A Comparison Between Three-Point Dixon Sequences and Label Fusion Techniques for Water-Fat Separation in High-Field MRI Local SAR Estimation. Torrado-Carvajal A, Abaci Turk E, Herraiz JL, Eryaman Y, Hernandez-Tamames JA, Adalsteinsson E, Wald LL, and Malpica N Annual Meeting of ISMRM 2015
A Fast Patch-Based Approach for Pseudo-CT Generation from MRI T1-Weighted Images: A Potential Solution for PET/MR Attenuation Correction. Torrado-Carvajal A, Alcain E, Herraiz JL, Montemayor AS, Hernandez-Tamames JA, Adalsteinsson E, Wald LL, and Malpica N Annual Meeting of ISMRM 2015
Disclosures
Radio Frequency Applications of Dipole Antennas in High Field MRI (MIT 15547J)
2013 ISMRM, Magna Award (Yigitcan): Combined Loop + Dipole Arrays for 7 T Brain Imaging. Eryaman, Yigitcan; Guérin, Bastien; Kosior, Robert; Adalsteinsson, Elfar; Wald, Lawrence L.
2014 ISMRM, Magna Award (Yigitcan): A Simulation Based Validation of a PTx Pulse Design Strategy Using Implant-Friendly Modes for Patients with DBS Implants. Eryaman, Yigitcan; Guerin, Bastien; Akgun, Can; Herraiz, Joaquin L.; Martin, Adrian; Torrado-Carvajal, Angel; Malpica, Norberto; Hernández-Tamamés, J. A.; Schiavi, Emanuele; Adalsteinsson, Elfar; Wald, Lawrence
2014 ISMRM, Magna Award (Angel): A Multi-Atlas and Label Fusion Approach for Patient-Specific MRI Based Skull Segmentation. Torrado-Carvajal A, Hernandez-Tamames JA, Herraiz JL, Eryaman Y, Rozenholc Y, Adalsteinsson E,Wald LL,Norberto Malpica N.
2015 ISMRM, Magna Award (Angel): A Fast Patch-Based Approach for Pseudo-CT Generation from MRI T1-Weighted Images: A Potential Solution for PET/MR Attenuation Correction. Torrado-Carvajal A, Alcain E, Herraiz JL, Montemayor AS, Hernandez-Tamames JA, Adalsteinsson E, Wald LL, and Malpica N
Media and updates
In June 2014, Team MS-SAR Team member Joaquín López Herraiz presented to the Biomedical Innovation Conference in Madrid: